The authors of my article should read the consent to genetic counseling and testing.
First of all, they should understand that Hemoglobin F is switching to Hemoglobin S. This will enlighten them that the context they want to illuminate is upside down.
First of all, AS and AS if they get married and the woman gets pregnant, they have a probability of having offspring with sickle cell disease 25% (1:4). And even if the child in the womb has sickle cell, it will not be the cause of miscarriage.
The first mistake is to suggest that the pregnancy is just because their son has sickle cell.
Sickle cell is not a problem for the child in the mother’s womb because,e at this time,e all his hemoglobin is F or other embryonic hemoglobins.
Only after the baby is born and about three to six months will hemoglobin F change to hemoglobin S.
It is only at this stage that sickle cell disease appears to be effective. The second mistake is to allow the doctor of Labarina to counsel Mainasara.
Counseling is done so that couples can understand their risk of contracting the disease or spreading it to their offspring.
The first thing that the counselor is taught is that he should never interfere in the choices that the couple will make for themselves. And the married couple is brought together in o,ne p, lace and they are not given a satisfactory exp, lamination and then they go to discuss among themselves.
It is wrong to show that the doctor singled out the husband and told him that they should either stop having children or divorce. This is not his job. It is not a scientific advice, especially if they are already married – they did not come to premarital genetic counseling and testing before marriage.
What the doctor will do here is to inform them that they have a 25% risk of having offspring with sickle cell every time the woman gets pregnant. And here is the task of raising a sickle cell patient. Here are the things that should be done by parents.
Like Mainasara, since they are rich, they can do IVF and give them embryo selection and choose one that does not have sickle cells and implant them. In some countries, they can do prenatal screening if the fetus has sickle cell and have an abortion when it is very young.
Third thing, they can do newborn screening if he has sickle cell and start planning to give him a stem cell transplant or gene therapy to cure him. If all that is not possible, there are modern drugs that strengthen the health of sickle cell patients – some of them are currently being researched.
All this information should be shown to the couple so that they can choose. It is a mistake to say that the woman will not give birth just because she and her husband have AS. Please fix it in advance.
HERE IS THE RESPONSE OF THE AUTHOR OF THE PROGRAM From Yakubu M. Kumo Dr, he opened his information, and it was greatly expanded, although many things hup burp ought are in the story.
Now the problem has started, which will continue to be followed slowly, most of the studies by Dr he brought will be found in it, because it has been researched before putting pen to writing, except for human imperfections, there must be one or two mistakes, especially since there is no doctor in the whole crew of my story.
We rely on research and questioning, and sometimes, asking whether it is wrong can be wrong.
Indeed, the possibility of having a child with sickle cell disease for AS+AS couples is 24%, or 1/4, that is one in four children, but Dr.
He did not explain that the children can be unlucky whether they are ten and all of them come with the disease, or all of them come without the disease or some get it and some lose it.
For this reason, even religious scholars advise not to have a marriage or if it is divorce, the children will be born with the disease, especially when the law is always to save lives. (Hifz al Nafs) or to guard against wasting wealth in treatment (Hifz al Maal).
Although Dr. He said that Mainasara has a property that can be aborted early if it is understood that the pregnancy, is carrying the disease or the disease can be removed while the child is still in the womb.
I want to say Dr. He said whether there is any danger in doing so or not, but as long as the story is followed, it will be seen how all these issues were brought up, I don’t want to reveal the progress. Just keep watching.
The doctor is said to have interfered in a work that is not his, and he will be told not to enter the cattle shed again, even though he sees himself as a relative or advisor to Mainasara.
Alh Mainasaran also warned him from there if he did not forget. We are very grateful to Dr. Ibrahim Musa, and this information you have provided will be useful even in future projects, God willing.
We continue to be corrected, they also look at us and make excuses.
What can you say about this challenge and the response?
